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Fact Sheet: Flourescence In Situ Hybridization (FISH)

Fact Sheet: Flourescence In Situ Hybridization (FISH)

Fluorescence in situ hybridization (FISH) provides researchers with a way to visualize and map the genetic material in an individual's cells, including specifc genes or portions of genes. This is important for understanding a variety of chromosomal abnormalities and other genetic mutations. Unlike most other techniques used to study chromosomes, FISH does not have to be performed on cells that are actively dividing. This makes it a very versatile procedure.


Credit: Darryl Leja , NHGRI.



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